1018946-38-7
1018946-38-7
Chemical Structure
MDR-1339
Synonym(s): DWK-1339
- CAS No.: 1018946-38-7
- Formula:C20H22O4
- Molecular Weight:326.39
IUPAC Name: 2-(3,4-dimethoxyphenyl)-5-(3-methoxypropyl)benzofuran
InChIKey: CUEPJIGXQLIOIK-UHFFFAOYSA-N
SMILES: COCCCC1=CC=C(OC(C2=CC=C(OC)C(OC)=C2)=C3)C3=C1
Biological Activity: MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer's disease.
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MDR-1339 | 99.95% | MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer's disease. | ||||||||||||||||||||
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4'-Methylchrysoeriol | 99.17% | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. | ||||||||||||||||||||
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6,3'-Dimethoxyflavone | 6,3'-Dimethoxyflavone is the pyrolytic compound of Lignin (HY-111830). | |||||||||||||||||||||
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Moracin B | Moracin B is a phytoalexin with antifungal activity. Moracin B can be isolated from the cortex and phloem tissues of mulberry (Morus alba Linne) infected with Fusarium solani f. sp. mori. Moracin B can be used to study plant disease resistance mechanisms against microbial infections, particularly showing potential application value in the field of plant disease control. | |||||||||||||||||||||
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Gnetofuran B | Gnetofuran B is a natural product. | |||||||||||||||||||||
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Cabreuvin | 98.08% | Cabreuvin is an isoflavonoid compound that can be isolated and extracted from Calopogonium mucunoides. Cabreuvin has a weak inhibitory activity against urease. | ||||||||||||||||||||
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7,3',4'-Tri-O-methylluteolin | 99.20% | 7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities. | ||||||||||||||||||||
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Ailanthoidol | Ailanthoidol is a natural occurring neolignan, with anti-inflammatory and antitumor activities. Ailanthoidol has chemopreventive activity against tumor promotion. | |||||||||||||||||||||
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3',4'-Dimethoxyflavone (Standard) | ≥98% | 3',4'-Dimethoxyflavone is a lipophilic flavone, can be isolated from the leaves of Primula veris. 3',4'-Dimethoxyflavone can reduce the synthesis and accumulation of PARP and protect cortical neurones against cell death induced by Parthanatos. 3',4'-Dimethoxyflavone is also an aryl hydrocarbon receptor antagonist in human breast cancer cells. 3',4'-Dimethoxyflavone can promote the proliferation of human hematopoietic stem cells. 3',4'-Dimethoxyflavone has various biological activities, including antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidaemic, and neuroprotective or neurotrophic effects. | ||||||||||||||||||||
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3′,4′,5′-Trimethoxyflavone | 3’,4’,5’-Trimethoxyflavone is a biochemical reagent. | |||||||||||||||||||||
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4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol | 4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol is a Lignans product that can be isolated from the herbs of Diospyros lotus. | |||||||||||||||||||||
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