102-32-9
102-32-9
Chemical Structure
3,4-Dihydroxybenzeneacetic acid
- CAS No.: 102-32-9
- Formula:C8H8O4
- Molecular Weight:168.15
IUPAC Name: 2-(3,4-dihydroxyphenyl)acetic acid
InChIKey: CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES: OC1=C(O)C=CC(CC(O)=O)=C1
Biological Activity: 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
3,4-Dihydroxybenzeneacetic acid | 99.90% | 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxybenzeneacetic acid (Standard) | 99.88% | 3,4-Dihydroxybenzeneacetic acid (Standard) is the analytical standard of 3,4-Dihydroxybenzeneacetic acid. This product is intended for research and analytical applications. 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxybenzeneacetic acid-d3 | 3,4-Dihydroxybenzeneacetic acid-d3 is deuterium-labeled 3,4-Dihydroxybenzeneacetic acid (HY-W001080). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxybenzeneacetic acid-13C,18O2 | 3,4-Dihydroxybenzeneacetic acid-13C,18O2 is the 13C- and 18O-labeled labeled 3,4-Dihydroxybenzeneacetic acid (HY-W001080). 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxybenzeneacetic acid-d5 | 98.67% | 3,4-Dihydroxybenzeneacetic acid-d5 is the deuterium labeled 3,4-Dihydroxybenzeneacetic acid. 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Homogentisic acid | 99.68% | Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as Aβ1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Homogentisic acid-13C6 | 98.57% | Homogentisic acid-13C6 is the 13C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dopamine-d5 hydrochloride | 99.6% | Dopamine-d5 (hydrochloride) is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Protocatechuic acid | 99.98% | Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA-d6 | 99.48% | L-DOPA-d6 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Homovanillic acid | 99.96% | Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Homovanillic acid-d5 | 99.0% | Homovanillic acid-d5 (Vanilacetic acid-d5) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2,4-Dihydroxyphenylacetic acid | 95.44% | 2,4-Dihydroxyphenylacetic acid (compound 3) is a natural product that can be obtained from Nigella damascene L. seeds. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Hydroxyphenylacetic acid-d6 | 99.16% | 4-Hydroxyphenylacetic acid-d6 is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dihydrocaffeic acid (Standard) | 99.88% | Dihydrocaffeic acid (Standard) (3,4-Dihydroxy-benzenepropanoic acid (Standard)) is the analytical standard of Dihydrocaffeic acid (HY-N2406). This product is intended for research and analytical applications. Dihydrocaffeic acid is a microbial metabolite of flavonoids. Dihydrocaffeic acid scavenges intracellular ROS and increases nitric oxide synthase activity. Dihydrocaffeic acid reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Dihydrocaffeic acid has antioxidant, anti-inflammatory and anti-cartilage degradation activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
DL-Norepinephrine-d6 hydrochloride | 98.5% | DL-Norepinephrine-d6 hydrochloride is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is an external racemic catecholamine neurotransmitter, which is an equal mixture of the left-handed (L-, with activity) and right-handed (D-, with very low or no activity) stereoisomers. DL-Norepinephrine hydrochloride after being labeled with tritium can be used as a tracer for the research on Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
DL-Norepinephrine-d6 | 96.25% | DL-Norepinephrine-d6 is the deuterium labeled DL-Norepinephrine. DL-Norepinephrine is an external racemic catecholamine neurotransmitter, which is an equal mixture of the left-handed (L-, with activity) and right-handed (D-, with very low or no activity) stereoisomers. DL-Norepinephrine after being labeled with tritium can be used as a tracer for the research on Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3-Chloro-4-hydroxyphenylacetic acid | 3-Chloro-4-hydroxyphenylacetic acid is a fungal metabolite. 3-Chloro-4-hydroxyphenylacetic acid is an active small molecule, that can be used as building block in synthesis of 17β-HSD2 inhibitors. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methyl 3,4-dihydroxyphenylacetate | 98.50% | Methyl 3,4-dihydroxyphenylacetate is a potent enterovirus 71 (EV71) infection inhibitor. Methyl 3,4-dihydroxyphenylacetate inhibits EV71 replication in rhabdomyosarcoma (RD) cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxyphenylpyruvic acid | 3,4-Dihydroxyphenylpyruvic acid is a nucleoside metabolite. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-(1,2-Dihydroxyethyl)benzene-1,2-diol-d5 | 4-(1,2-Dihydroxyethyl)benzene-1,2-diol-d5 is the deuterium labeled 4-(1,2-Dihydroxyethyl)benzene-1,2-diol (HY-W010066). 4-(1,2-Dihydroxyethyl)benzene-1,2-diol, a normal norepinephrine metabolite, is found to be associated with Menkes syndrome. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Hydroxy-3-nitrophenylacetic acid-d5 | 4-Hydroxy-3-nitrophenylacetic acid-d5 is the deuterium labeled 4-Hydroxy-3-nitrophenylacetic acid (HY-W001085). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Homovanillic Acid-13C6 | Homovanillic Acid-13C6 (Vanilacetic acid-13C6) is the 13C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2,6-Dihydroxybenzoic acid-d3 | 2,6-Dihydroxybenzoic acid-d3 is the deuterated-labeled 2,6-Dihydroxybenzoic acid (HY-Y0801). 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
