1029713-99-2
1029713-99-2
Chemical Structure
CNJ-294
- CAS No.: 1029713-99-2
- Formula:C22H15FN6O
- Molecular Weight:398.39
InChIKey: ZSOSTTWEQBUFFE-UHFFFAOYSA-N
SMILES: O=C(C1=C(F)C=C(C2=NN3C(N=C2)=NC=C3CC4=CC5=CC=CN=C5C=C4)C=C1)N
Biological Activity: CNJ-294 is an intermediate in the synthesis of Capmatinib (HY-13404) and a metabolite of Capmatinib (HY-13404)[1][2].
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CNJ-294 | CNJ-294 is an intermediate in the synthesis of Capmatinib (HY-13404) and a metabolite of Capmatinib (HY-13404). | |||||||||||||||||||||
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References
- [1]. Qingquan Lian. Preparation method of carbamatinib. CN111825678 A. 2020-10-27.
- [2]. Glaenzel U, et al. Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite. Drug Metab Dispos. 2020 Oct;48(10):873-885. [Content Brief]
