103-73-1
103-73-1
Chemical Structure
Ethoxybenzene
- CAS No.: 103-73-1
- Formula:C8H10O
- Molecular Weight:122.17
IUPAC Name: ethoxybenzene
InChIKey: DLRJIFUOBPOJNS-UHFFFAOYSA-N
SMILES: CCOC1=CC=CC=C1
Biological Activity: Ethoxybenzene is a SARM1 NAD+ hydrolase inhibitor (human SARM1 IC50 = 0.385 μM). Ethoxybenzene co-crystallizes with the SARM1 TIR domain and exhibits an edge-to-face aromatic interaction with Trp638. Ethoxybenzene can be used in research on SARM1-related axonal degeneration[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ethoxybenzene | 99.65% | Ethoxybenzene is a SARM1 NAD+ hydrolase inhibitor (human SARM1 IC50 = 0.385 μM). Ethoxybenzene co-crystallizes with the SARM1 TIR domain and exhibits an edge-to-face aromatic interaction with Trp638. Ethoxybenzene can be used in research on SARM1-related axonal degeneration. | ||||||||||||||||||||
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References
- [1]. Li S, et al. Design, synthesis, and activity evaluation of 2-iminobenzimidazoles as c-Myc inhibitors for treating multiple myeloma. Heliyon. 2024 Apr 15;10(7):e28411.
- [2]. Giroud M, et al. Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy. Journal of medicinal chemistry. 2025 Mar 27;68(6):6558-6575. [Content Brief]
