1031727-34-0
Chemical Structure
14-Norpseurotin A
Synonym(s): 14-Norpseurotin
- CAS No.: 1031727-34-0
- Formula:C21H23NO8
- Molecular Weight:417.41
IUPAC Name: (5S,8S,9R)-8-benzoyl-2-((1S,2S,Z)-1,2-dihydroxypent-3-en-1-yl)-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione
InChIKey: FCGCMRDADMTJIM-LFDIKFNASA-N
SMILES: O=C(N1)[C@@](OC([C@@H](O)[C@@H](O)/C=C\C)=C2C)(C2=O)[C@@H](O)[C@]1(OC)C(C3=CC=CC=C3)=O
Biological Activity: 14-Norpseurotin A (14-Norpseurotin) is an Antibacterial, antimalarial, and anticancer agent. 14-Norpseurotin A is isolated from various fungi of the Aspergillus genus. 14-Norpseurotin A induces neurite outgrowth. 14-Norpseurotin A inhibits the growth of Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus. 14-Norpseurotin A exhibits antileishmanial activity against L. donovani, antiplasmodial activity against P. falciparum, and shows no activity against T. cruzi. 14-Norpseurotin A exerts anticancer activity against breast cancer. 14-Norpseurotin A is used in research related to leishmaniasis, malaria, and breast cancer[1][2][3].
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14-Norpseurotin A | 14-Norpseurotin A (14-Norpseurotin) is an Antibacterial, antimalarial, and anticancer agent. 14-Norpseurotin A is isolated from various fungi of the Aspergillus genus. 14-Norpseurotin A induces neurite outgrowth. 14-Norpseurotin A inhibits the growth of Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus. 14-Norpseurotin A exhibits antileishmanial activity against L. donovani, antiplasmodial activity against P. falciparum, and shows no activity against T. cruzi. 14-Norpseurotin A exerts anticancer activity against breast cancer. 14-Norpseurotin A is used in research related to leishmaniasis, malaria, and breast cancer. | |||||||||||||||||||||
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References
- [1]. Ge HM, et al. Bioactive alkaloids from endophytic Aspergillus fumigatus. Journal of natural products. 2009 Apr;72(4):753-5. [Content Brief]
- [2]. Martínez-Luis S, et al. Antiparasitic and anticancer constituents of the endophytic fungus Aspergillus sp. strain F1544. Natural product communications. 2012 Feb;7(2):165-8.
- [3]. Zhang M, et al. Cytotoxic alkaloids and antibiotic nordammarane triterpenoids from the marine-derived fungus Aspergillus sydowi. Journal of natural products. 2008 Jun;71(6):985-9. [Content Brief]
