1031977-31-7
1031977-31-7
Chemical Structure
D359-0396
- CAS No.: 1031977-31-7
- Formula:C24H24N4O2
- Molecular Weight:400.47
InChIKey: NYQHEGVGLCCWEM-UHFFFAOYSA-N
SMILES: O=C1C2=CN3C4=C(NC(C3=C2N(C)C(N1C)=O)C5=CC=C(C(C)C)C=C5)C=CC=C4
Biological Activity: D359-0396 is an orally active NLRP3 inflammasome inhibitor. D359-0396 inhibits pyroptosis and IL-1β release in macrophages. D359-0396 also inhibits the oligomerization of NLRP3, ASC and the cleavage of GSDMD. D359-0396 alleviates EAE, and also improves survival after septic shock in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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D359-0396 | 99.98% | D359-0396 is an orally active NLRP3 inflammasome inhibitor. D359-0396 inhibits pyroptosis and IL-1β release in macrophages. D359-0396 also inhibits the oligomerization of NLRP3, ASC and the cleavage of GSDMD. D359-0396 alleviates EAE, and also improves survival after septic shock in mice. | ||||||||||||||||||||
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