1032714-06-9
Chemical Structure
Dopamine D2 receptor antagonist-3
- CAS No.: 1032714-06-9
- Formula:C18H17F4N5
- Molecular Weight:379.35
IUPAC Name: 6-((1-(3-fluoro-5-(trifluoromethyl)benzyl)piperidin-4-yl)amino)pyridazine-3-carbonitrile
InChIKey: BNFVPEAUEULETE-UHFFFAOYSA-N
SMILES: FC1=CC(CN2CCC(NC3=NN=C(C#N)C=C3)CC2)=CC(C(F)(F)F)=C1
Biological Activity: Dopamine D2 receptor antagonist-3 (Example 17) is an orally active and selective dopamine D2 receptor antagonist with a pIC50 of 5.52. Dopamine D2 receptor antagonist-3 exhibits antipsychotic activity in the Apomorphine (HY-12723) induced agitation in rats. Dopamine D2 receptor antagonist-3 can be used for psychiatric and neurological disorders research[1].
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Dopamine D2 receptor antagonist-3 | Dopamine D2 receptor antagonist-3 (Example 17) is an orally active and selective dopamine D2 receptor antagonist with a pIC50 of 5.52. Dopamine D2 receptor antagonist-3 exhibits antipsychotic activity in the Apomorphine (HY-12723) induced agitation in rats. Dopamine D2 receptor antagonist-3 can be used for psychiatric and neurological disorders research. | |||||||||||||||||||||
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