1035094-10-0
1035094-10-0
Chemical Structure
Iloprost-d4
- CAS No.: 1035094-10-0
- Formula:C22H28D4O4
- Molecular Weight:364.51
IUPAC Name: 5-((3aS,4R,5R,6aS,E)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic-2,2,3,3-d4 acid
InChIKey: HIFJCPQKFCZDDL-KFJXZQTLSA-N
SMILES: C(=C/[C@H](C(CC#CC)C)O)\[C@@H]1[C@@]2([C@@](C/C(=C\CC(C(C(O)=O)([2H])[2H])([2H])[2H])/C2)(C[C@H]1O)[H])[H]
Biological Activity: Iloprost-d4 (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].
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Iloprost-d4 | Iloprost-d4 (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2. | |||||||||||||||||||||
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Iloprost (Standard) | ≥98% | Iloprost (Standard) is the analytical standard of Iloprost. This product is intended for research and analytical applications. Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research. | ||||||||||||||||||||
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Iloprost | 99.06% | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Della Bella S, et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecules. Prostaglandins Other Lipid Mediat. 2001 Jun;65(2-3):73-83. [Content Brief]
