103548-82-9
103548-82-9
Chemical Structure
Huperzine B
- CAS No.: 103548-82-9
- Formula:C16H20N2O
- Molecular Weight:256.34
IUPAC Name: (4aR,5R,10bR)-12-methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one
InChIKey: YYWGABLTRMRUIT-HWWQOWPSSA-N
SMILES: CC1=C[C@]2([H])[C@]3([H])[C@](C(C=CC4=O)=C(N4)C2)(NCCC3)C1
Biological Activity: Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease[1][2].
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Huperzine B | 98.73% | Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease. | ||||||||||||||||||||
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Huperzine B (Standard) | ≥98% | Huperzine B (Standard) is the analytical standard of Huperzine B. This product is intended for research and analytical applications. Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease. | ||||||||||||||||||||
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References
- [1]. Zhang HY, et al. Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells. Neurosci Lett. 2000 Sep 29;292(1):41-4. [Content Brief]
- [2]. He XC, et al. Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B. Bioorg Med Chem. 2007 Feb 1;15(3):1394-408. [Content Brief]
