1036271-54-1
Chemical Structure
JC-D7
- CAS No.: 1036271-54-1
- Formula:C28H31BrCl2N4O
- Molecular Weight:590.38
InChIKey: DSNPFMKJUXAPGB-IERUDJENSA-N
SMILES: O=C(CCCCC[N+]1=C(/C=C/C2=CC=CC3=C2C=CC=C3)N(C)C4=C1C=C(C(Cl)=C4)Cl)NCCN.[Br-]
Biological Activity: JC-D7 is a benzimidazolium-based fluorescent polyphosphate (polyP)-specific probe and dye used for detecting, localizing, and quantifying inorganic polyP stores. JC-D7 specifically labels in vitro synthesized polyP as well as endogenous polyP in living cells, and enables real-time detection of polyP release from lysosomes. The detection conditions for JC-D7 are Ex/Em = 390/535 nm, 390/530 nm, 405/535 nm, and 405/480-510 nm[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JC-D7 | 99.03% | JC-D7 is a benzimidazolium-based fluorescent polyphosphate (polyP)-specific probe and dye used for detecting, localizing, and quantifying inorganic polyP stores. JC-D7 specifically labels in vitro synthesized polyP as well as endogenous polyP in living cells, and enables real-time detection of polyP release from lysosomes. The detection conditions for JC-D7 are Ex/Em = 390/535 nm, 390/530 nm, 405/535 nm, and 405/480-510 nm. | ||||||||||||||||||||
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References
- [1]. Angelova PR, et al. In situ investigation of mammalian inorganic polyphosphate localization using novel selective fluorescent probes JC-D7 and JC-D8. ACS chemical biology. 2014 Sep 19;9(9):2101-10.
- [2]. Deitert A, et al. Rapid Fluorescence Assay for Polyphosphate in Yeast Extracts Using JC-D7. Yeast (Chichester, England). 2024 Oct;41(10):593-604.
- [3]. Yang X, et al. Quantification of Polyphosphate in Environmental Planktonic Samples Using a Novel Fluorescence Dye JC-D7. Environ Sci Technol. 2024;58:14249–14259.
- [4]. Zhu J, et al. A genetically validated approach for detecting inorganic polyphosphates in plants. The Plant journal : for cell and molecular biology. 2020 May;102(3):507-516.
