1036730-46-7
Chemical Structure
C450-0730
- CAS No.: 1036730-46-7
- Formula:C23H28ClN3O4S
- Molecular Weight:478.00
IUPAC Name: 2-((1-acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide
InChIKey: BXNBAWRWAXBDOG-UHFFFAOYSA-N
SMILES: CC(C)CC(NS(=O)(C1=CC2=C(N(C(C)=O)CC2)C=C1)=O)C(NCC3=CC=C(Cl)C=C3)=O
Biological Activity: C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant[1].
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C450-0730 | 97.0% | C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant. | ||||||||||||||||||||
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