1036759-00-8
Chemical Structure
SW116 free base
- CAS No.: 1036759-00-8
- Formula:C39H56N4O5S
- Molecular Weight:692.95
IUPAC Name: (1R,3r,5S)-9-(10-((5-(dimethylamino)naphthalene)-1-sulfonamido)decyl)-9-azabicyclo[3.3.1]nonan-3-yl (2-methoxy-5-methylphenyl)carbamate
InChIKey: ZSJGAYGQEFMTOD-OZDAUYEJSA-N
SMILES: O=[S](NCCCCCCCCCCN([C@]1([H])C2)[C@@](CCC1)([H])C[C@@H]2OC(NC(C=C3C)=C(C=C3)OC)=O)(C4=CC=CC5=C4C=CC=C5N(C)C)=O
Biological Activity: SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research[1].
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SW116 free base | SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research. | |||||||||||||||||||||
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