1041644-43-2
1041644-43-2
Chemical Structure
Nec-4
- CAS No.: 1041644-43-2
- Formula:C15H13ClFN3O
- Molecular Weight:305.73
IUPAC Name: (S)-N-(1-(2-chloro-6-fluorophenyl)ethyl)-5-cyano-1-methyl-1H-pyrrole-2-carboxamide
InChIKey: OVRPUVGBRNDNAS-VIFPVBQESA-N
SMILES: C[C@@H](C1=C(C=CC=C1Cl)F)NC(C2=CC=C(N2C)C#N)=O
Biological Activity: Nec-4, a tricyclic derivative, is a potent receptor interacting protein 1 (RIP1) inhibitor, with an IC50 of 2.6 μM, Ki of 0.46 μM.
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Nec-4 | Nec-4, a tricyclic derivative, is a potent receptor interacting protein 1 (RIP1) inhibitor, with an IC50 of 2.6 μM, Ki of 0.46 μM. | |||||||||||||||||||||
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