1043489-40-2
1043489-40-2
Chemical Structure
RO5192022
- CAS No.: 1043489-40-2
- Formula:C9H8F2N2O
- Molecular Weight:198.17
InChIKey: KARCBPLVDTUMJH-MRVPVSSYSA-N
SMILES: NC1=N[C@H](CO1)C2=CC=C(C=C2F)F
Biological Activity: RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia[1][2].
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RO5192022 | RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia. | |||||||||||||||||||||
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References
- [1]. Revel FG, et al.. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 2011 May 17;108(20):8485-90. [Content Brief]
- [2]. Aleksandrov AA, et al.. The TAAR5 agonist α-NETA causes dyskinesia in mice. Neuroscience letters. 2019 Jun 21;704:208-211. [Content Brief]
