1043865-37-7
Chemical Structure
CO probe 1
- CAS No.: 1043865-37-7
- Formula:C26H18Cl2O5
- Molecular Weight:481.32
IUPAC Name: 3',6'-bis(allyloxy)-2',7'-dichloro-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
InChIKey: UMDPDHOQNTZXTC-UHFFFAOYSA-N
SMILES: O=C1OC2(C3=CC(Cl)=C(C=C3OC4=CC(OCC=C)=C(C=C42)Cl)OCC=C)C5=C1C=CC=C5
Biological Activity: CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd2+ to Pd0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CO probe 1 | 99.88% | CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd2+ to Pd0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer. | ||||||||||||||||||||
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