104486-81-9
104486-81-9
Chemical Structure
Mupirocin calcium
Synonym(s): BRL-4910A calcium; Pseudomonic acid calcium
- CAS No.: 104486-81-9
- Formula:C26H44CaO9
- Molecular Weight:520.66
SMILES: O[C@@H]([C@H]([C@H](C/C(C)=C/C(OCCCCCCCCC(O)=O)=O)OC1)O)[C@@]1([H])C[C@H]2[C@@]([C@@H](C)[C@@H](O)C)([H])O2.[1/2].[Ca]
Biological Activity: Mupirocin (BRL-4910A, Pseudomonic acid) calcium is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2].
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Mupirocin calcium | Mupirocin (BRL-4910A, Pseudomonic acid) calcium is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis. | |||||||||||||||||||||
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References
- [1]. Sutherland R, et al. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Antimicrob Agents Chemother. 1985 Apr;27(4):495-8. [Content Brief]
- [2]. Parenti MA, et al. Mupirocin: a topical antibiotic with a unique structure and mechanism of action. Clin Pharm. 1987 Oct;6(10):761-70. [Content Brief]
