104542-46-3
Chemical Structure
Urdamycin B
- CAS No.: 104542-46-3
- Formula:C37H44O13
- Molecular Weight:696.74
IUPAC Name: (R)-9-((2R,4R,5R,6R)-4-(((2S,5S,6S)-5-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-3,8-dihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione
InChIKey: RVYIFZVNJLDNAV-VSYBRGMMSA-N
SMILES: O=C1C2=C(C(C3=C(O)C([C@H]4C[C@H]([C@@H]([C@H](O4)C)O)O[C@@H]5O[C@H]([C@H](CC5)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O)C)=CC=C31)=O)C=CC(C[C@@](O)(C7)C)=C2C7=O
Biological Activity: Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections[1][2].
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Urdamycin B | Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections. | |||||||||||||||||||||
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References
- [1]. DRAUTZ H, et al. METABOLIC PRODUCTS OF MICROORGANISMS. 234 URDAMYCINS, NEW ANGUCYCLINE ANTIBIOTICS FROM STREPTOMYCES FRADIAE I. ISOLATION, CHARACTERIZATION AND BIOLOGICAL PROPERTIES[J]. The Journal of Antibiotics, 1986, 39(12): 1657-1669.
- [2]. Rohr J, et al. Metabolic products of microorganisms. 240. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. II. Structural studies of urdamycins B to F. J Antibiot (Tokyo). 1987 Apr;40(4):459-67. [Content Brief]
