1049800-47-6
1049800-47-6
Chemical Structure
SIRT1 activator 4
- CAS No.: 1049800-47-6
- Formula:C24H17FO2
- Molecular Weight:356.40
IUPAC Name: (E)-2-(1-([1,1'-biphenyl]-4-ylmethylene)-5-fluoro-1H-inden-3-yl)acetic acid
InChIKey: VJDZAFANKNWYHT-XDHOZWIPSA-N
SMILES: C(=C\1/C=2C(C(CC(O)=O)=C1)=CC(F)=CC2)\C3=CC=C(C=C3)C4=CC=CC=C4
Biological Activity: SIRT1 activator 4 is an orally active, NAD+-independent SIRT1 activator. SIRT1 activator 4 is also an analog of (E)-2'-desmethyl Sulindac (HY-B0008), with weak or negligible inhibitory activity against COX-1 and no inhibitory activity against COX-2. SIRT1 activator 4 can be used for the research of metabolic diseases[1].
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SIRT1 activator 4 | SIRT1 activator 4 is an orally active, NAD+-independent SIRT1 activator. SIRT1 activator 4 is also an analog of (E)-2'-desmethyl Sulindac (HY-B0008), with weak or negligible inhibitory activity against COX-1 and no inhibitory activity against COX-2. SIRT1 activator 4 can be used for the research of metabolic diseases. | |||||||||||||||||||||
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