105026-81-1
105026-81-1
Chemical Structure
N-Octanoyl dopamine
- CAS No.: 105026-81-1
- Formula:C16H25NO3
- Molecular Weight:279.37
IUPAC Name: N-(3,4-dihydroxyphenethyl)octanamide
InChIKey: MGRVMTGNRVNIEL-UHFFFAOYSA-N
SMILES: CCCCCCCC(NCCC1=CC=C(O)C(O)=C1)=O
Biological Activity: N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells[1][2].
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N-Octanoyl dopamine | N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells. | |||||||||||||||||||||
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References
- [1]. Sivakkanan Loganathan, et al. N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. Pharmacol Res. 2019 Dec:150:104503. [Content Brief]
- [2]. Björn B Hofmann, et al. N-Octanoyl-Dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells. Sci Rep. 2019 Dec 18;9(1):19338. [Content Brief]
