1054549-73-3
1054549-73-3
Chemical Structure
6-CEPN
- CAS No.: 1054549-73-3
- Formula:C23H18O5
- Molecular Weight:374.39
IUPAC Name: (E)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-styrylchroman-4-one
InChIKey: WBONVHMXTSZBAF-IZZDOVSWSA-N
SMILES: O=C1CC(OC2=C1C(O)=C(C(O)=C2)/C=C/C3=CC=CC=C3)C4=CC=C(C=C4)O
Biological Activity: 6-CEPN is a RAS inhibitor. 6-CEPN can inhibit RAS activation by binding to Icmt binding sites. 6-CEPN has anticancer activity. 6-CEPN can block cancer cells in the G1 phase. 6-CEPN can induce autophagy and necrosis of Cancer cells (Icmt: isovalerylcysteine carboxymethyltransferase)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6-CEPN | 99.17% | 6-CEPN is a RAS inhibitor. 6-CEPN can inhibit RAS activation by binding to Icmt binding sites. 6-CEPN has anticancer activity. 6-CEPN can block cancer cells in the G1 phase. 6-CEPN can induce autophagy and necrosis of Cancer cells (Icmt: isovalerylcysteine carboxymethyltransferase). | ||||||||||||||||||||
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References
- [1]. Zhao Y, et al. 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells[J].European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR), 2016, 68(Null). [Content Brief]
