105462-25-7
105462-25-7
Chemical Structure
NE58043
- CAS No.: 105462-25-7
- Formula:C7H11NO7P2
- Molecular Weight:283.11
IUPAC Name: (1-hydroxy-2-(pyridin-4-yl)ethane-1,1-diyl)bis(phosphonic acid)
InChIKey: ZWHKKFUMEGWCKH-UHFFFAOYSA-N
SMILES: O=P(O)(O)C(O)(CC=1C=CN=CC1)P(=O)(O)O
Biological Activity: NE58043 (Compound 21) is a nitrogen-containing bisphosphonate compound. NE58043 has no significant inhibitory activity against Entamoeba histolytica and Plasmodium falciparum with IC50 > 200 μM. NE58043 shows a LD50 of 171 μM for human nasopharyngeal carcinoma KB cells. NE58043 can be used for the research of cancer and infection, such as nasopharyngeal carcinoma[1].
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NE58043 | NE58043 (Compound 21) is a nitrogen-containing bisphosphonate compound. NE58043 has no significant inhibitory activity against Entamoeba histolytica and Plasmodium falciparum with IC50 > 200 μM. NE58043 shows a LD50 of 171 μM for human nasopharyngeal carcinoma KB cells. NE58043 can be used for the research of cancer and infection, such as nasopharyngeal carcinoma. | |||||||||||||||||||||
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