1055329-49-1
Chemical Structure
Sutherlandioside D
- CAS No.: 1055329-49-1
- Formula:C36H58O9
- Molecular Weight:634.84
InChIKey: SWNUBPWWSLUXMU-MVNMJQGYSA-N
SMILES: O=C1[C@]23[C@@]4(C3)[C@]([C@H](C[C@@]2([H])C(C)(C=C1)C)O)([H])[C@]5([C@](CC4)([C@@](CC5)([H])[C@H](C)CC[C@H](O)C(C)(C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C)C
Biological Activity: Sutherlandioside D is a natural product present in the aerial parts of Sutherlandia frutescens. Sutherlandioside D acts as an inhibitor of the Gli/hedgehog signaling pathway and exhibits reactive oxygen species (ROS) regulatory activity. Sutherlandioside D inhibits Gli reporter gene activity and reduces ROS production. Sutherlandioside D can be used in prostate cancer-related research[1][2][3].
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Sutherlandioside D | Sutherlandioside D is a natural product present in the aerial parts of Sutherlandia frutescens. Sutherlandioside D acts as an inhibitor of the Gli/hedgehog signaling pathway and exhibits reactive oxygen species (ROS) regulatory activity. Sutherlandioside D inhibits Gli reporter gene activity and reduces ROS production. Sutherlandioside D can be used in prostate cancer-related research. | |||||||||||||||||||||
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References
- [1]. Avula B, et al. Quantitative determination of flavonoids and cycloartanol glycosides from aerial parts of Sutherlandia frutescens (L.) R. BR. by using LC-UV/ELSD methods and confirmation by using LC-MS method. J Pharm Biomed Anal. 2010 Jun 5;52(2):173-80.
- [2]. Lin H, et al. Inhibition of Gli/hedgehog signaling in prostate cancer cells by "cancer bush" Sutherlandia frutescens extract. Cell biology international. 2016 Feb;40(2):131-42. [Content Brief]
- [3]. Lei W, et al. Unveiling the anti-inflammatory activity of Sutherlandia frutescens using murine macrophages. International immunopharmacology. 2015 Dec;29(2):254-262.
