1063714-11-3
Chemical Structure
CXL 017
- CAS No.: 1063714-11-3
- Formula:C24H27NO7
- Molecular Weight:441.47
IUPAC Name: ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
InChIKey: YCQHMLQVIFMCCE-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)OC2=C(C=C(C3=CC(OC)=CC(OC)=C3)C=C2)C1CC(OCC)=O)OCC
Biological Activity: CXL 017 is a sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) inhibitor. CXL 017 can inhibit the ATPase activity of SERCA by competing with ATP for binding. CXL 017 exhibits selective cytotoxicity against multidrug-resistant acute myeloid leukemia cells HL60/MX2. CXL 017 can be used in the research of tumors such as multidrug-resistant acute myeloid leukemia[1].
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CXL 017 | CXL 017 is a sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) inhibitor. CXL 017 can inhibit the ATPase activity of SERCA by competing with ATP for binding. CXL 017 exhibits selective cytotoxicity against multidrug-resistant acute myeloid leukemia cells HL60/MX2. CXL 017 can be used in the research of tumors such as multidrug-resistant acute myeloid leukemia. | |||||||||||||||||||||
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