1065109-28-5
1065109-28-5
Chemical Structure
PF-4522654
- CAS No.: 1065109-28-5
- Formula:C16H18F2N4
- Molecular Weight:304.34
IUPAC Name: 2-(difluoro(phenyl)methyl)-N-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
InChIKey: XYHWHDGNYCZFTQ-UHFFFAOYSA-N
SMILES: FC(C1=NC(CCNCC2)=C2C(NC)=N1)(C3=CC=CC=C3)F
Biological Activity: PF-4522654 is a potent, selective and brain-permeable 5-HT2C receptor agonist with an EC50 of 16 nM and a Ki of 8 nM. PF-4522654 shows no measurable functional agonism at no 5-HT2A and 5-HT2B receptors. PF-4522654 can be used for the study of stress urinary incontinence (SUI)[1].
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PF-4522654 | PF-4522654 is a potent, selective and brain-permeable 5-HT2C receptor agonist with an EC50 of 16 nM and a Ki of 8 nM. PF-4522654 shows no measurable functional agonism at no 5-HT2A and 5-HT2B receptors. PF-4522654 can be used for the study of stress urinary incontinence (SUI). | |||||||||||||||||||||
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