1065481-24-4
1065481-24-4
Chemical Structure
(E)-N-(2-Fluorophenyl)cinnamamide
- CAS No.: 1065481-24-4
- Formula:C15H12FNO
- Molecular Weight:241.27
IUPAC Name: N-(2-fluorophenyl)cinnamamide
InChIKey: GFAVMCPSQILRPK-ZHACJKMWSA-N
SMILES: N(C(/C=C/C1=CC=CC=C1)=O)C2=C(F)C=CC=C2
Biological Activity: (E)-N-(2-Fluorophenyl) cinnamamide (Compound 5m) is a MMP-2 and MMP-9 inhibitor, with selectivity over MMP-1. Its IC50 values against MMP-2, MMP-9 and MMP-1 are 9.09 nM, 8.02 nM and 4117.53 nM, respectively. (E)-N-(2-Fluorophenyl) cinnamamide can be used in the research of metastatic tumors[1].
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(E)-N-(2-Fluorophenyl)cinnamamide | (E)-N-(2-Fluorophenyl) cinnamamide (Compound 5m) is a MMP-2 and MMP-9 inhibitor, with selectivity over MMP-1. Its IC50 values against MMP-2, MMP-9 and MMP-1 are 9.09 nM, 8.02 nM and 4117.53 nM, respectively. (E)-N-(2-Fluorophenyl) cinnamamide can be used in the research of metastatic tumors. | |||||||||||||||||||||
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