1073560-68-5
Chemical Structure
E3 ligase Ligand 10
- CAS No.: 1073560-68-5
- Formula:C47H52N4O7
- Molecular Weight:784.94
IUPAC Name: (S)-2-((S)-1-((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoic acid
InChIKey: GZMLKDJDSMXRGP-HCVICXAGSA-N
SMILES: OC([C@@H](NC([C@H]1N(CCC1)C([C@H](C2CCCCC2)NC([C@@H](N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)C)=O)=O)=O)C(C6=CC=CC=C6)C7=CC=CC=C7)=O
Biological Activity: E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
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E3 ligase Ligand 10 | E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. | |||||||||||||||||||||
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