107978-77-8
Chemical Structure
Fibronectin Type III Connecting Segment Fragment 1-25
- CAS No.: 107978-77-8
- Formula:C123H195N31O39
- Molecular Weight:2732.05
SMILES: C([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCC(O)=O)=O)CC(C)C)=O)CCC2)CCC(N)=O)=O)CC(C)C)=O)C(C)C)=O)[C@@H](C)O)=O)CC(C)C)=O)CCC1)CC3=CN=CN3)(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(NCC(=O)N6[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N7[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CO)=O)CCC7)C(C)C)=O)CC(O)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCC6)=O)=O)CC(C)C)=O)CC(N)=O)=O)CCC4
Biological Activity: Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken[1][2].
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Fibronectin Type III Connecting Segment Fragment 1-25 | Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken. | |||||||||||||||||||||
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References
- [1]. A Komoriya, et al. The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine. J Biol Chem. 1991 Aug 15;266(23):15075-9. [Content Brief]
- [2]. M J Humphries, et al. Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment. J Cell Biol. 1988 Apr;106(4):1289-97. [Content Brief]
