108005-94-3
Chemical Structure
Cathepsin L-IN-2
Synonym(s): (Rac)-Z-Phe-Phe-FMK
- CAS No.: 108005-94-3
- Formula:C27H27FN2O4
- Molecular Weight:462.51
IUPAC Name: benzyl (1-((4-fluoro-3-oxo-1-phenylbutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
InChIKey: CAILNONEKASNSH-UHFFFAOYSA-N
SMILES: O=C(OCC1=CC=CC=C1)NC(CC2=CC=CC=C2)C(NC(CC3=CC=CC=C3)C(CF)=O)=O
Biological Activity: Cathepsin L-IN-2 ((Rac)-Z-Phe-Phe-FMK) is a Cathepsin L (CTSL) inhibitor. Cathepsin L-IN-2 inhibits CTSL enzymatic activity, supporting the mechanism by which CTSL mediates T-DXd linker cleavage and payload release. Cathepsin L-IN-2 is used in studies on Cathepsin L-dependent ADC payload release and breast cancer-related mechanisms[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cathepsin L-IN-2 | 98.02% | Cathepsin L-IN-2 ((Rac)-Z-Phe-Phe-FMK) is a Cathepsin L (CTSL) inhibitor. Cathepsin L-IN-2 inhibits CTSL enzymatic activity, supporting the mechanism by which CTSL mediates T-DXd linker cleavage and payload release. Cathepsin L-IN-2 is used in studies on Cathepsin L-dependent ADC payload release and breast cancer-related mechanisms. | ||||||||||||||||||||
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