1092521-74-8
Chemical Structure
Farnesyl thiosalicylic acid amide
Synonym(s): FTS amide; Salirasib amide
- CAS No.: 1092521-74-8
- Formula:C22H31NOS
- Molecular Weight:357.55
IUPAC Name: 2-(((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)benzamide
InChIKey: GZTMFRUGZMZCRD-CFBAGHHKSA-N
SMILES: C/C(C)=C/CC/C(C)=C/CC/C(C)=C/CSC1=C(C=CC=C1)C(N)=O
Biological Activity: Farnesyl thiosalicylic acid amide (FTS-A) is an orally active derivative of farnesyl thiosalicylic acid (HY-14754). Farnesyl thiosalicylic acid amide reduces Ras-GTP levels and inhibits cell growth with IC50s of 20 and 10 μM for Panc-1 and U87 cells, respectively. Farnesyl thiosalicylic acid amide can be used for the research of cancer[1].
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Farnesyl thiosalicylic acid amide | Farnesyl thiosalicylic acid amide (FTS-A) is an orally active derivative of farnesyl thiosalicylic acid (HY-14754). Farnesyl thiosalicylic acid amide reduces Ras-GTP levels and inhibits cell growth with IC50s of 20 and 10 μM for Panc-1 and U87 cells, respectively. Farnesyl thiosalicylic acid amide can be used for the research of cancer. | |||||||||||||||||||||
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