1092939-17-7
1092939-17-7
Chemical Structure
Ruxolitinib phosphate
Synonym(s): INCB018424 phosphate
- CAS No.: 1092939-17-7
- Formula:C17H21N6O4P
- Molecular Weight:404.36
IUPAC Name: (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate
InChIKey: JFMWPOCYMYGEDM-XFULWGLBSA-N
SMILES: N#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2.O=P(O)(O)O
Biological Activity: Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC50s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ruxolitinib phosphate | 99.92% | Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC50s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3. | ||||||||||||||||||||
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Ruxolitinib phosphate (Standard) | ≥98% | Ruxolitinib phosphate (Standard) is the analytical standard of Ruxolitinib phosphate (HY-50858). This product is intended for research and analytical applications. Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC50s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3. | ||||||||||||||||||||
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