1093082-54-2
1093082-54-2
Chemical Structure
Renin inhibitor-1
- CAS No.: 1093082-54-2
- Formula:C22H30N4O4
- Molecular Weight:414.50
IUPAC Name: methyl (R)-(3-(3-((N-cyclopropylmorpholine-2-carboxamido)methyl)-1H-indol-1-yl)propyl)carbamate
InChIKey: NIPWZZBPFRFZBX-HXUWFJFHSA-N
SMILES: O=C(OC)NCCCN1C=C(CN(C2CC2)C([C@H]3CNCCO3)=O)C4=C1C=CC=C4
Biological Activity: Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases[1].
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Renin inhibitor-1 | Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases. | |||||||||||||||||||||
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