1095173-64-0
1095173-64-0
Chemical Structure
Glasdegib hydrochloride
Synonym(s): PF-04449913 hydrochloride
- CAS No.: 1095173-64-0
- Formula:C21H23ClN6O
- Molecular Weight:410.90
SMILES: CN1[C@H](C[C@@H](CC1)NC(NC2=CC=C(C=C2)C#N)=O)C3=NC4=CC=CC=C4N3.Cl
Biological Activity: Glasdegib hydrochloride is a potent and orally bioavailable smoothened inhibitor. Glasdegib hydrochloride (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM[1].
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Glasdegib hydrochloride | Glasdegib hydrochloride is a potent and orally bioavailable smoothened inhibitor. Glasdegib hydrochloride (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM. | |||||||||||||||||||||
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