109621-29-6
109621-29-6
Chemical Structure
Phenylaminojuglone AJ-2
- CAS No.: 109621-29-6
- Formula:C16H11NO3
- Molecular Weight:265.26
InChIKey: KTEVSOYDEBXIGZ-UHFFFAOYSA-N
SMILES: O=C1C=C(C(C2=C(C=CC=C12)O)=O)NC3=CC=CC=C3
Biological Activity: Phenylaminojuglone AJ-2 is a nitric oxide synthase inhibitor that interacts with soluble guanylate cyclase, β-adrenergic receptor, CaV1.2 calcium channel, KV channel and KCa channel. Phenylaminojuglone AJ-2 blocks extracellular Ca2+ influx, regulates the activity of the NO?sGC?cGMP signaling pathway, and inhibits pharmacologic and electromechanical contractions of smooth muscle. Phenylaminojuglone AJ-2 is applicable to studies related to intestinal spasm[1].
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Phenylaminojuglone AJ-2 | Phenylaminojuglone AJ-2 is a nitric oxide synthase inhibitor that interacts with soluble guanylate cyclase, β-adrenergic receptor, CaV1.2 calcium channel, KV channel and KCa channel. Phenylaminojuglone AJ-2 blocks extracellular Ca2+ influx, regulates the activity of the NO?sGC?cGMP signaling pathway, and inhibits pharmacologic and electromechanical contractions of smooth muscle. Phenylaminojuglone AJ-2 is applicable to studies related to intestinal spasm. | |||||||||||||||||||||
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