1098-92-6
1098-92-6
Chemical Structure
3-Hydroxy-5,7,4′-trimethoxyflavone
- CAS No.: 1098-92-6
- Formula:C18H16O6
- Molecular Weight:328.32
IUPAC Name: 3-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
InChIKey: SGPXJCVFCJANKN-UHFFFAOYSA-N
SMILES: COC1=C2C(OC(C3=CC=C(OC)C=C3)=C(O)C2=O)=CC(OC)=C1
Biological Activity: 3-Hydroxy-5,7,4′-trimethoxyflavone is a flavonol can be isolated from Cucubalus baccifer (L.)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Hydroxy-5,7,4′-trimethoxyflavone | 98.46% | 3-Hydroxy-5,7,4′-trimethoxyflavone is a flavonol can be isolated from Cucubalus baccifer (L.). | ||||||||||||||||||||
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3-Hydroxy-5,7,4′-trimethoxyflavone (Standard) | ≥98% | 3-Hydroxy-5,7,4′-trimethoxyflavone (Standard) is the analytical standard of 3-Hydroxy-5,7,4′-trimethoxyflavone (HY-N3432). This product is intended for research and analytical applications. 3-Hydroxy-5,7,4′-trimethoxyflavone is a flavonol can be isolated from Cucubalus baccifer (L.). | ||||||||||||||||||||
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3,5,7-Trimethoxyflavone | 98.86% | 3,5,7-Trimethoxyflavone, a flavonoid compound, can inhibit the TNF-α-induced high expression and secretion of MMP-1 by cells. 3,5,7-Trimethoxyflavone can be used to ameliorate skin damage. | ||||||||||||||||||||
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Tetramethylkaempferol | 99.93% | Tetramethylkaempferol is an antifungal agent. Tetramethylkaempferol shows antifungal activity against Candida albicansCandida albicans with an IC50 value of 17.63 µg/mL. | ||||||||||||||||||||
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Kaempferide (Standard) | 98.08% | Kaempferide (Standard) is the analytical standard of Kaempferide. This product is intended for research and analytical applications. | ||||||||||||||||||||
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7,4'-Dimethoxy-3-hydroxyflavone | 7,4'-Dimethoxy-3-hydroxyflavone is an orally active PAR4 antagonist. 7,4'-Dimethoxy-3-hydroxyflavone inhibits PAR4-mediated human platelet aggregation with an IC50 of 1.4 μM. 7,4'-Dimethoxy-3-hydroxyflavone inhibits PAR4-mediated human platelet aggregation and PAR4 signaling pathways, including NF-κB, Ca2+/protein kinase C, Akt, ERK and p38. 7,4'-Dimethoxy-3-hydroxyflavone prevents vascular PAR4 expression, endothelial dysfunction and ameliorates oxidative stress in Streptozotocin (STZ) (HY-13753)-induced diabetic mice. 7,4'-Dimethoxy-3-hydroxyflavone prevents thrombosis in mice without affecting bleeding time. | |||||||||||||||||||||
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Kaempferol 5-methyl ether | Kaempferol 5-methyl ether (5-O-Methylkaempferol) is a flavonoid compound. Kaempferol 5-methyl ether can be isolated from the geopropolis of Melipona subnitida. | |||||||||||||||||||||
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Rhamnocitrin | 99.38% | Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells). | ||||||||||||||||||||
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Mikanin | Mikanin is a natural product. | |||||||||||||||||||||
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Kaempferol-7,4'-dimethyl ether | 98.42% | Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM. | ||||||||||||||||||||
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Kaempferol 3,7,4'-trimethyl ether | 99.97% | Kaempferol 3,7,4'-trimethyl ether is an O-methylated kaempferol flavonol aglycone distributed in Siparuna gigantotepala, Aframomum arundinaceum and Siparuna guianensis. Kaempferol 3,7,4'-trimethyl ether exhibits antioxidant activity. Kaempferol 3,7,4'-trimethyl ether suppresses the proliferation of leukemia cells and exerts selective cytotoxicity against both drug‑sensitive and multi‑factorial drug‑resistant cancer cells. Kaempferol 3,7,4'-trimethyl ether can be applied in the research of multidrug‑resistant cancers. | ||||||||||||||||||||
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5,7,4'-Trimethoxyflavone (Standard) | ≥98% | 5,7,4'-Trimethoxyflavone (Standard) is the analytical standard of 5,7,4'-Trimethoxyflavone. This product is intended for research and analytical applications. 5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress. | ||||||||||||||||||||
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