1105659-16-2
1105659-16-2
Chemical Structure
INHIB1X
- CAS No.: 1105659-16-2
- Formula:C23H21FN4O
- Molecular Weight:388.44
InChIKey: XZZOJFOFCDHYRX-UHFFFAOYSA-N
SMILES: O=C1NCC2(CN(C2)C)C3=C1C4=C(C5=CC(C6=C(F)C=CC=C6)=NC=C5CC4)N3
Biological Activity: INHIB1X is a tetracyclic MAPKAP-K2 (MK2) inhibitor with an IC50 of 0.02 μM. INHIB1X inhibits LPS-induced TNFα release in human peripheral blood mononuclear cells (hPBMCs). INHIB1X suppresses the phosphorylation of hsp27 in Anisomycin-stimulated THP-1 cells. INHIB1X can be used for the research of inflammatory and tumor diseases[1].
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INHIB1X | INHIB1X is a tetracyclic MAPKAP-K2 (MK2) inhibitor with an IC50 of 0.02 μM. INHIB1X inhibits LPS-induced TNFα release in human peripheral blood mononuclear cells (hPBMCs). INHIB1X suppresses the phosphorylation of hsp27 in Anisomycin-stimulated THP-1 cells. INHIB1X can be used for the research of inflammatory and tumor diseases. | |||||||||||||||||||||
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