1106675-81-3
Chemical Structure
17-Hydroxypregnenolone sulfate sodium
- CAS No.: 1106675-81-3
- Formula:C21H31NaO6S
- Molecular Weight:434.52
InChIKey: RHRYJGCZEAMVTR-AFCSUKBBSA-M
SMILES: C[C@@]12[C@](CC[C@]2(O)C(C)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)OS(=O)(O[Na])=O)=CC3)C
Biological Activity: 17-Hydroxypregnenolone sulfate sodium is a key intermediate in adrenal and gonadal steroidogenesis. 17-Hydroxypregnenolone sulfate sodium acts as a precursor in the biosynthesis of steroid hormones (e.g., glucocorticoids, sex hormones). 17-Hydroxypregnenolone sulfate sodium is promising for research of adrenal function development and neurosteroid-related diseases (e.g., cognitive impairment, neurodegenerative diseases) [1][2][3].
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17-Hydroxypregnenolone sulfate sodium | 17-Hydroxypregnenolone sulfate sodium is a key intermediate in adrenal and gonadal steroidogenesis. 17-Hydroxypregnenolone sulfate sodium acts as a precursor in the biosynthesis of steroid hormones (e.g., glucocorticoids, sex hormones). 17-Hydroxypregnenolone sulfate sodium is promising for research of adrenal function development and neurosteroid-related diseases (e.g., cognitive impairment, neurodegenerative diseases) . | |||||||||||||||||||||
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References
- [1]. Shimozawa K, et al. Age-related changes in serum 17-hydroxypregnenolone and 17-hydroxypregnenolone sulfate concentrations in human infancy and childhood. Endocrinol Jpn. 1988 Apr;35(2):189-95. [Content Brief]
- [2]. Hu D, et al. Biosynthesis of triterpenoid natural products[J]. Comprehensive Natural Products III, 2020: 577-612.
- [3]. Qaiser MZ, et al. Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat. J Neurochem. 2017 Sep;142(5):672-685. [Content Brief]
