111-86-4
111-86-4
Chemical Structure
Octylamine
Synonym(s): n-Octylamine
- CAS No.: 111-86-4
- Formula:C8H19N
- Molecular Weight:129.24
IUPAC Name: octan-1-amine
InChIKey: IOQPZZOEVPZRBK-UHFFFAOYSA-N
SMILES: NCCCCCCCC
Biological Activity: Octylamine (n-Octylamine) is a positive effector of FMO. Octylamine interacts with oxidized cytochrome P-450 to produce a type II difference spectrum that is blocked by carbon monoxide. Octylamine enhances N-deacetyl ketoconazole-induced LDH leakage in cell cultures, but does not interfere with the LDH assay. Octylamine can be used in hepatotoxicity research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Octylamine | 99.79% | Octylamine (n-Octylamine) is a positive effector of FMO. Octylamine interacts with oxidized cytochrome P-450 to produce a type II difference spectrum that is blocked by carbon monoxide. Octylamine enhances N-deacetyl ketoconazole-induced LDH leakage in cell cultures, but does not interfere with the LDH assay. Octylamine can be used in hepatotoxicity research. | ||||||||||||||||||||
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References
- [1]. Kulkarni AP, et al. An unusual effect of N-octylamine on the cytochrome b5 spectrum of insect and mammalian microsomes. Chemico-biological interactions. 1977 May;17(2):223-37.
- [2]. Rodriguez RJ, et al. N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. Toxicology. 1997 Feb 28;117(2-3):123-31.
- [3]. Shen X, et al. In vitro stability and cytotoxicity analysis of liposomes anchored with octylamine-graft-poly (aspartic). RSC advances. 2016 Jun 16;6(63):58034-45.
- [4]. Xu G, et al. Octylamine-Modified Cellulose Nanocrystal-Enhanced Stabilization of Pickering Emulsions for Self-Healing Composite Coatings. ACS applied materials & interfaces. 2022 Mar 16;14(10):12722-12733.
