1110781-88-8
1110781-88-8
Chemical Structure
Ro 5212773
Synonym(s): EPPTB
- CAS No.: 1110781-88-8
- Formula:C20H21F3N2O2
- Molecular Weight:378.39
IUPAC Name: N-(3-ethoxyphenyl)-4-(pyrrolidin-1-yl)-3-(trifluoromethyl)benzamide
InChIKey: KLFVWQCQUXXLOU-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(OCC)=C1)C2=CC=C(N3CCCC3)C(C(F)(F)F)=C2
Biological Activity: Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids[1][2].
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Ro 5212773 | 99.85% | Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids. | ||||||||||||||||||||
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Ro 5212773 (Standard) | ≥98% | Ro 5212773 (Standard) is the analytical standard of Ro 5212773 (HY-110098). This product is intended for research and analytical applications. Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids. | ||||||||||||||||||||
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