111112-18-6
Chemical Structure
LY-195448 hydrochloride
- CAS No.: 111112-18-6
- Formula:C20H27ClN2O2
- Molecular Weight:362.89
IUPAC Name: (R)-4-(3-((2-hydroxy-2-phenylethyl)amino)-3-methylbutyl)benzamide hydrochloride
InChIKey: PFTVHDSGCARRKR-FERBBOLQSA-N
SMILES: NC(C(C=C1)=CC=C1CCC(C)(C)NC[C@@H](C2=CC=CC=C2)O)=O.Cl
Biological Activity: LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of "standard" side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor.
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LY-195448 hydrochloride | LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of "standard" side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor. | |||||||||||||||||||||
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