1112994-35-0
1112994-35-0
Chemical Structure
P-2281
- CAS No.: 1112994-35-0
- Formula:C9H8ClN3O
- Molecular Weight:209.63
IUPAC Name: 2-chloro-N-(6-cyanopyridin-3-yl)propanamide
InChIKey: VFOLQYOVUCHHET-UHFFFAOYSA-N
SMILES: CC(C(NC1=CC=C(N=C1)C#N)=O)Cl
Biological Activity: P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis[1].
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P-2281 | 99.81% | P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis. | ||||||||||||||||||||
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