1119503-63-7
1119503-63-7
Chemical Structure
JNc-440
- CAS No.: 1119503-63-7
- Formula:C26H24N4O3
- Molecular Weight:440.50
IUPAC Name: N-(3-(2,2-diphenylacetamido)propyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide
InChIKey: VMRVWMQQRPXUQU-UHFFFAOYSA-N
SMILES: O=C(C(N1)=NC2=C(C=CC=C2)C1=O)NCCCNC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O
Biological Activity: JNc-440 is a potent antihypertensive agent. JNc-440 can enhance the interaction of TRPV4 and Ca2+-activated potassium channel 3 (KCa2.3) in endothelial cells. JNc-440 can also enhance vasodilation, and exerted antihypertensive effects in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JNc-440 | 98.04% | JNc-440 is a potent antihypertensive agent. JNc-440 can enhance the interaction of TRPV4 and Ca2+-activated potassium channel 3 (KCa2.3) in endothelial cells. JNc-440 can also enhance vasodilation, and exerted antihypertensive effects in mice. | ||||||||||||||||||||
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