112243-88-6
112243-88-6
Chemical Structure
epi-D-Captopril
Synonym(s): epi-D-SQ 14225
- CAS No.: 112243-88-6
- Formula:C9H15NO3S
- Molecular Weight:217.29
InChIKey: FAKRSMQSSFJEIM-NKWVEPMBSA-N
SMILES: SC[C@H](C)C(N1[C@H](CCC1)C(O)=O)=O
Biological Activity: epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril (HY-B0368) and an inhibitor of metallo-β-lactamases (MBLs). The IC50 values of epi-D-Captopril against NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. epi-D-Captopril is expected to be used in the research of diseases caused by MBLs-related drug-resistant bacterial infections[1].
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epi-D-Captopril | epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril (HY-B0368) and an inhibitor of metallo-β-lactamases (MBLs). The IC50 values of epi-D-Captopril against NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. epi-D-Captopril is expected to be used in the research of diseases caused by MBLs-related drug-resistant bacterial infections. | |||||||||||||||||||||
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