112946-90-4
Chemical Structure
(-)-SA2572
- CAS No.: 112946-90-4
- Formula:C32H41ClN2O6S
- Molecular Weight:617.20
IUPAC Name: (S)-1-(2-(5-methoxy-2-(4-(methyl(3,4,5-trimethoxyphenethyl)amino)butoxy)phenyl)benzo[d]thiazol-3(2H)-yl)ethan-1-one hydrochloride
InChIKey: AONMOOKWGFXUKH-UCRKPPETSA-N
SMILES: CC(N1[C@H](C2=C(C=CC(OC)=C2)OCCCCN(C)CCC3=CC(OC)=C(C(OC)=C3)OC)SC4=CC=CC=C41)=O.Cl
Biological Activity: (-)-SA2572 is an orally active Ca2+ inward channel inhibitor. (-)-SA2572 inhibits the slow Ca2+ inward channel and the fast Na+ inward channel. (-)-SA2572 inhibits depolarization-induced contraction of gastrointestinal smooth muscle and vascular smooth muscle, prolongs atrioventricular nodal conduction time, and inhibits His bundle-ventricular conduction time. (-)-SA2572 reduces systolic blood pressure in spontaneously hypertensive rats. (-)-SA2572 can be used in the research of hypertension[1].
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(-)-SA2572 | (-)-SA2572 is an orally active Ca2+ inward channel inhibitor. (-)-SA2572 inhibits the slow Ca2+ inward channel and the fast Na+ inward channel. (-)-SA2572 inhibits depolarization-induced contraction of gastrointestinal smooth muscle and vascular smooth muscle, prolongs atrioventricular nodal conduction time, and inhibits His bundle-ventricular conduction time. (-)-SA2572 reduces systolic blood pressure in spontaneously hypertensive rats. (-)-SA2572 can be used in the research of hypertension. | |||||||||||||||||||||
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