1142015-13-1
Chemical Structure
(S)-FTY-720 Vinylphosphonate
- CAS No.: 1142015-13-1
- Formula:C20H34NO4P
- Molecular Weight:383.46
IUPAC Name: (S,E)-(3-amino-3-(hydroxymethyl)-5-(4-octylphenyl)pent-1-en-1-yl)phosphonic acid
InChIKey: YWQUROWPKWKDNA-APHAIJBRSA-N
SMILES: O=P(O)(O)/C=C/[C@@](CO)(N)CCC1=CC=C(C=C1)CCCCCCCC
Biological Activity: (S)-FTY-720 Vinylphosphonate is a chiral phosphonate analogue of Fingolimod (HY-11063). (S)-FTY-720 Vinylphosphonate can activate the S1P1 receptor with an EC50 value of 75 nM. (S)-FTY-720 Vinylphosphonate can significantly inhibit Camptothecin (HY-16560)-induced apoptosis in IEC-6 cells. (S)-FTY-720 Vinylphosphonate is applicable for the research of autoimmune diseases[1].
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(S)-FTY-720 Vinylphosphonate | (S)-FTY-720 Vinylphosphonate is a chiral phosphonate analogue of Fingolimod (HY-11063). (S)-FTY-720 Vinylphosphonate can activate the S1P1 receptor with an EC50 value of 75 nM. (S)-FTY-720 Vinylphosphonate can significantly inhibit Camptothecin (HY-16560)-induced apoptosis in IEC-6 cells. (S)-FTY-720 Vinylphosphonate is applicable for the research of autoimmune diseases. | |||||||||||||||||||||
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