114528-81-3
114528-81-3
Chemical Structure
(+)-U-50488 hydrochloride
Synonym(s): (+)-Trans-(1R,2R)-U-50488 hydrochloride
- CAS No.: 114528-81-3
- Formula:C19H27Cl3N2O
- Molecular Weight:405.79
IUPAC Name: 2-(3,4-dichlorophenyl)-N-methyl-N-((1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl)acetamide hydrochloride
InChIKey: KGMMGVIYOHGOKQ-JAXOOIEVSA-N
SMILES: O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl
Biological Activity: (+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997)[1].
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(+)-U-50488 hydrochloride | (+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997). | |||||||||||||||||||||
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