1146534-45-3
Chemical Structure
Aminohexylgeldanamycin hydrochloride
Synonym(s): AHGDM hydrochloride
- CAS No.: 1146534-45-3
- Formula:C34H53ClN4O8
- Molecular Weight:681.26
IUPAC Name: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((6-aminohexyl)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate hydrochloride
InChIKey: KIDYRDGTJBAQHJ-CZSHERGUSA-N
SMILES: [H]Cl.O=C(C(NCCCCCCN)=C1C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(C)\C2=O)C=C(N2)C1=O
Biological Activity: Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities[1].
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Aminohexylgeldanamycin hydrochloride | Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities. | |||||||||||||||||||||
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