1147524-83-1
1147524-83-1
Chemical Structure
Zileuton sulfoxide
- CAS No.: 1147524-83-1
- Formula:C11H12N2O3S
- Molecular Weight:252.29
IUPAC Name: 1-hydroxy-1-(1-(1-oxidobenzo[b]thiophen-2-yl)ethyl)urea
InChIKey: KWEAXQJUQDQMNY-UHFFFAOYSA-N
SMILES: O=C(N)N(O)C(C1=CC2=CC=CC=C2S1=O)C
Biological Activity: Zileuton sulfoxide is a sulfoxide derivative of Zileuton (HY-14164), a potent and selective inhibitor of lipoxygenase 5-LOX with anti-asthmatic properties[1][2].
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Zileuton sulfoxide | Zileuton sulfoxide is a sulfoxide derivative of Zileuton (HY-14164), a potent and selective inhibitor of lipoxygenase 5-LOX with anti-asthmatic properties. | |||||||||||||||||||||
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References
- [1]. Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10 [Content Brief] [Content Brief]
- [2]. Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner [Content Brief] [Content Brief]
