114753-71-8
114753-71-8
Chemical Structure
Khl 8430
- CAS No.: 114753-71-8
- Formula:C25H29NO2
- Molecular Weight:375.50
InChIKey: UWKOIXGMEPYUTC-UHFFFAOYSA-N
SMILES: COC1=CC(C(C)NCCC(C2=CC=CC=C2)C3=CC=CC=C3)=CC=C1OC
Biological Activity: Khl 8430 is a Calmodulin antagonist. It binds to both free calmodulin and calmodulin-enzyme complexes, thereby abolishing the regulatory effects of calmodulin on phosphofructokinase (PFA) and phosphodiesterase. Khl 8430 is applicable for studies of calmodulin-related signaling pathways[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Khl 8430 | Khl 8430 is a Calmodulin antagonist. It binds to both free calmodulin and calmodulin-enzyme complexes, thereby abolishing the regulatory effects of calmodulin on phosphofructokinase (PFA) and phosphodiesterase. Khl 8430 is applicable for studies of calmodulin-related signaling pathways. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Orosz F, et al. Dissimilar mechanisms of action of anticalmodulin drugs: quantitative analysis. Molecular pharmacology. 1990 Dec;38(6):910-6.
- [2]. Orosz F, et al. The interaction of a new anti-tumour drug, KAR-2 with calmodulin. British journal of pharmacology. 1997 Jul;121(5):955-62. [Content Brief]
-
[3]. Krisztina Takács-Novák, et al. Potentiometric pKa determination of water-insoluble compounds: validation study in methanol/water mixtures, International Journal of Pharmaceutics, Volume 151, Issue 2, 1997, Pages 235-248, ISSN 0378-5173.
