114932-60-4
Chemical Structure
1-Pyrenebutyric acid N-hydroxysuccinimide ester
- CAS No.: 114932-60-4
- Formula:C24H19NO4
- Molecular Weight:385.41
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 4-(pyren-1-yl)butanoate
InChIKey: YBNMDCCMCLUHBL-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CCCC2=C(C3=C45)C=CC5=CC=CC4=CC=C3C=C2
Biological Activity: 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Pyrenebutyric acid N-hydroxysuccinimide ester | 99.93% | 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry. | ||||||||||||||||||||
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References
- [1]. Benvidi A, et al. Comparison of impedimetric detection of DNA hybridization on the various biosensors based on modified glassy carbon electrodes with PANHS and nanomaterials of RGO and MWCNTs. Talanta. 2016 Jan 15;147:621-7. [Content Brief]
- [2]. Tian J, et al. Biosensing platform based on graphene oxide via self-assembly induced by synergic interactions. Anal Biochem. 2014 Sep 1;460:16-21. [Content Brief]
- [3]. Stefansson S, et al. Targeting antibodies to carbon nanotube field effect transistors by pyrene hydrazide modification of heavy chain carbohydrates[J]. Journal of Nanotechnology, 2012, 2012(1): 490175.
- [4]. Fapyane D, et al. Graphitized-Carbon-Nanofiber Paper-Enzyme Electrode Fabrication Through Non-Covalent Modification for Enzyme Biofuel Cell Application. J Biomed Nanotechnol. 2015 Jan;11(1):137-42. [Content Brief]
- [5]. Khandelwal V, et al. Graphene biosensor: Rapid and Accurate diagnostic method of COVID-19 (SARS-CoV-2). 2020.
- [6]. Sakamoto H, et al. Development of biofuel cell using a complex of highly oriented immobilized his-tagged enzyme and carbon nanotube surface through a pyrene derivative. Journal of Nanoscience and Nanotechnology, 2019, 19(6): 3551-3557.
