115166-32-0
Chemical Structure
Grandinin
- CAS No.: 115166-32-0
- Formula:C46H34O30
- Molecular Weight:1066.74
InChIKey: BQQCUOQRZALHLB-UHFFFAOYSA-N
SMILES: O=C1OCC2OC(C3=CC(O)=C(C(O)=C3C4=C(C(O)=C(C5=C4C(OC(C2OC(C6=CC(O)=C(C(O)=C6C7=C(C(O)=C(C=C17)O)O)O)=O)C8OC(C9=C5C(O)=C(C(O)=C9C8C(C(C(C(CO)O)O)O)=O)O)=O)=O)O)O)O)=O
Biological Activity: Grandinin is a naturally occurring C-glucosidic ellagitannin with antitumor and anti-HSV activities. Grandinin exhibits selective cytotoxicity against human solid tumor cells. Grandinin inhibits the replication of HSV-1 and HSV-2 in Acyclovir (HY-17422)-resistant strains. Grandinin is used in research on melanoma and herpes simplex virus infection[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Grandinin | Grandinin is a naturally occurring C-glucosidic ellagitannin with antitumor and anti-HSV activities. Grandinin exhibits selective cytotoxicity against human solid tumor cells. Grandinin inhibits the replication of HSV-1 and HSV-2 in Acyclovir (HY-17422)-resistant strains. Grandinin is used in research on melanoma and herpes simplex virus infection. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Quideau S, et al. Ellagitannin chemistry. Chemical Reviews. 1996 Feb 1;96(1).
- [2]. Houston DMJ, et al. Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV. PloS one. 2017;12(6):e0179291.
- [3]. Vilhelmova-Ilieva N, et al. Ellagitannins as synergists of ACV on the replication of ACV-resistant strains of HSV 1 and 2. Antiviral research. 2014 Oct;110:104-14.
